Biomarker sensors and method for multi-color imaging and processing of single-molecule life signatures

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United States of America Patent

PATENT NO 8492160
SERIAL NO

12720103

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Abstract

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The invention is a device including array of aciive regions for use in reacting one or more species in at least two of the active regions in a sequential process, e.g., sequential reactions. The device has a transparent substrate member, which has a surface region and a silane material overlying the surface region. A first active region overlies a first portion of the silane material. The first region has a first dimension of less than 1 micron in size and has first molecules capable of binding to the first portion of the silane material. A second active region overlies a second portion of the silane material. The second region has a second dimension of less than 1 micron in size, second molecules capable of binding to the second portion of the active region, and a spatial distance separates the first active region and the second active region.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Collier, Charles Patrick Oak Ridge, US 12 295
Wade, Lawrence A La Canada, US 9 103

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