Transgeneic animal expressing a multiple mutated form of presenilin 1

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United States of America Patent

PATENT NO 8492610
SERIAL NO

10088139

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Abstract

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The present invention relates to the field of transgenic animal models and more particularly the animal models of Alzheimer's disease. The invention relates to a transgenic animal expressing a multimutated form of presenilin 1 and allowing an apoptotic phenomenon to be detected in a renewable peripheral tissue.

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Patent Owner(s)

Patent OwnerAddress
AVENTIS PHARMA S A20 AVENUE RAYMOND ARON ANTONY CEDEX 92165

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Czech, Christian Grenzach-Wyhlen, DE 12 63
Eckert, Anne Mannheim, DE 2 2
Muller, Walter Worms-Herrnsheim, DE 148 2987
Pradier, Laurent Verriéres, FR 17 95
Tremp, Gunter Palaiseau, FR 2 1

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