Methods and compositions for monitoring progression of huntington's disease

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8506957
APP PUB NO 20080286263A1
SERIAL NO

11792758

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a method of diagnosis of Huntington's Disease in a diagnostic sample of a valid body tissue taken from a human subject, which comprises detecting an altered concentration of a protein in the diagnostic sample, compared with a sample of a control human subject, the protein being selected from: Swiss Prot accession number: Protein name; P10909: Clusterin precursor; P00738: Haptoglobin precursor; P01009: Alpha-1-antitrypsin precursor; P01024: Complement C3 precursor; P01620: 1g kappa chain V-III region; P01834: 1 g kappa chain C region P01842: 1g lambda chain C regions; P01857: 1g gamma-1 chain C region; P01859: Ig gamma-2 chain C region; P01876: 1g alpha-1 chain C region P02647: Apolipoprotein A-I precursor; P02649: Apolipoprotein E precursor; P02652: Apolipoprotein A-II precursor; P02655: Apolipoprotein C-II precursor; P02656: Apolipoprotein C-II precursor P02671: Fibrinogen alpha/alpha-E chain precursor; P02763: Alpha-1-acid glycoprotein 1 precursor; P02766: Transthyretin precursor; P02768: Serum albumin precursor; P02787: Serotransferrin precursor; P04196: Histidine-rich glycoprotein precursor; P06727: Apolipoprotein A-IV precursor; P19652: Alpha-1-acid glycoprotein 2 precursor; P68871/P02042: Hemoglobin beta chain/Hemoglobin delta chain; P60709: Beta actin.

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Patent Owner(s)

Patent OwnerAddress
ELECTROPHORETICS LIMITEDLONDON WC1H 9BB

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Byers, Helen Louise London, GB 3 6
Campbell, James London, GB 78 436
Dalrymple, Annette London, GB 1 11
Leeds, Nicola Louise Tonbridge, GB 2 11
McGregor, Emma London, GB 3 13
Tabrizi, Sarah Joanna London, GB 1 11
Ward, Malcolm Andrew Shefford, GB 9 18
Westbrook, Jules Arthur Middlesex, GB 2 11

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