Methods of use for an antibody against human frizzled receptors 1, 2. 5, 7 or 8

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United States of America Patent

PATENT NO 8507442
APP PUB NO 20110318341A1
SERIAL NO

13164191

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Abstract

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Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.

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Patent Owner(s)

  • ONCOMED PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Axelrod, Fumiko Takada Palo Alto, US 24 329
Gurney, Austin L San Francisco, US 2150 9828
Hoey, Timothy Charles Hillsborough, US 36 437
Mitra, Satyajit Sujit Kumar South Pasadena, US 11 148
Sato, Aaron Ken Burlingame, US 32 392
Satyal, Sanjeev H San Carlos, US 18 203

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