Substituted thiazol-2-ylamine derivatives, pharmaceutical compositions, and methods of use as 11-beta HSD1 modulators

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United States of America Patent

PATENT NO 8513430
APP PUB NO 20120029029A1
SERIAL NO

13189640

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Abstract

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The present invention is directed to substituted thiazol-2-ylamine derivatives and pharmaceutically acceptable salts thereof that inhibit 11βHSD1 and that may be useful in the treatment of diseases in which modulation or inhibition of 11βHSD1 is beneficial or where a reduction in intracellular glucorticoid levels is desirable. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases, disorders, or conditions in which modulation or inhibition of 11βHSD1 is beneficial or where a reduction in intracellular glucorticoid levels is desirable.

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Patent Owner(s)

Patent OwnerAddress
VTVX HOLDINGS II LLC4170 MENDENHALL OAKS PKWY HIGH POINT NC 27265

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gupta, Suparna Greensboro, US 21 193
Polisetti, Dharma Rao High Point, US 60 1134

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