Humanized antibodies against LIGHT and uses thereof
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United States of America Patent
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Sep 3, 2013
Grant Date -
Apr 26, 2012
app pub date -
Mar 22, 2010
filing date -
Mar 24, 2009
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Abstract
The present invention is directed to antigen-binding polypeptides, or variants or derivatives thereof which specifically bind the LIGHT polypeptide. The invention is also directed to methods of making and using such antibodies specifically in the treatment or diagnosis of immune, inflammatory and malignant diseases or conditions (e.g. inflammatory bowel disease; Crohn's disease, ulcerative colitis, multiple sclerosis, rheumatoid arthritis and transplantation).
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