Peripheral opioid receptor antagonists and uses thereof
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United States of America Patent
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Oct 1, 2013
Grant Date -
Aug 4, 2011
app pub date -
Mar 28, 2008
filing date -
Mar 29, 2007
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Abstract
The present invention provides a compound of formula I: wherein R1, R2, R2′ and X′ are as defined and described herein, methods of manufacture thereof and compositions thereof, useful for example as peripheral mu opioid receptor antagonists in treatment of side effects of opioid administration.
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