Methods and apparatus for treating contrast nephropathy

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United States of America Patent

PATENT NO 8551069
APP PUB NO 20060271111A1
SERIAL NO

11368809

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Abstract

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Methods and apparatus are provided for treating contrast nephropathy, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

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Patent Owner(s)

Patent OwnerAddress
MEDTRONIC ARDIAN LUXEMBOURG S A R L2124 LUXEMBOURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deem, Mark Mountain View, US 162 18704
Demarais, Denise Los Gatos, US 65 25338
Gifford,, III Hanson Woodside, US 134 16224
Sutton, Douglas Pacifica, US 132 14377

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