Adenosine analogs and their use

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United States of America Patent

PATENT NO 8569259
APP PUB NO 20110237529A1
SERIAL NO

12515033

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are adenosine analog compounds of the general formula that act as P2Y receptors, e.g., the P2Y2 receptor, including pharmaceutical compositions; and uses thereof to treat or prevent diseases associated with that receptor, e.g., disorders relating to mucus secretion, such as cystic fibrosis, chronic obstructive pulmonary disorder (COPD), asthma, constipation, chronic idiopathic constipation, dry mouth (xerostomia), gum disease, and gastrointestinal problems caused by radiation and chemotherapy for cancer.

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Patent Owner(s)

  • MICRODOSE THERAPEUTX, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Becker, Oren Mevaseret Zion, IL 28 314
Ben-Zeev, Efrat K. Motzkin, IL 8 25
Jacques, Vincent Somerville, US 53 315
Marantz, Yael Kadma, IL 30 318
McCauley, Dilara Cambridge, US 56 901
Orbach, Pini Tel Mond, IL 11 114
Reddy, A Sekar Burlington, US 4 1
Saha, Ashis K Stow, US 20 637
Shacham, Sharon Chestnut Hill, US 67 1072
Xie, Michael Natick, US 132 2191
Zhang, Zhaoda Andover, US 23 138

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