Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids
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United States of America Patent
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Oct 29, 2013
Grant Date -
Aug 15, 2013
app pub date -
Dec 24, 2012
filing date -
Jun 27, 2003
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Abstract
Quaternary nitrogen heterocyclic boronic acid-containing compounds are described, which are sensitive to glucose and fructose, as well as a variety of other physiologically important analytes, such as aqueous chloride and iodide, and a method of using the compounds. Also disclosed is a contact lens doped with the quaternary nitrogen heterocyclic boronic acid-containing compound, and a method of using the doped contact lens to measure the concentration of analyte in tears under physiological conditions.
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