Imaging method and system using substrate functionalization
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United States of America Patent
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Nov 12, 2013
Grant Date -
Oct 4, 2012
app pub date -
Oct 13, 2010
filing date -
Oct 13, 2009
priority date (Note) -
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Abstract
An imaging system for analyzing fluorescent molecules in a sample, including a confocal microscope device, has a support in contact with at least a portion of the sample. In the system, the support surface in contact with the sample is functionalized so as to reduce the observation volume of the microscope on the surface in the axial direction. The present disclosure also relates to various uses of such a system as well as to a method for analyzing fluorescent molecules in a sample, the method being implemented by such a system.
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