Delivery device for dispensing pharmaceutical dosage forms into dissolution testing apparatus
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United States of America Patent
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Nov 19, 2013
Grant Date -
Jan 5, 2012
app pub date -
Jun 24, 2011
filing date -
Jun 30, 2010
priority date (Note) -
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Abstract
The present invention provides a dissolution test cell having a chamber and slide valve for dispensing pharmaceutical dosage forms, such as tablets, capsules, and powders, into the chamber without having to open the cell and expose the chamber and its contents to the ambient environment. The present invention also facilitates removal of a partially dissolved or non-disintegrating dosage form from the chamber and cell entirely, without exposing the interior of the cell and chamber. Dissolution test apparatus comprising at least one dissolution test cell in accordance with the invention is also provided, as well as methods for its operation to obtain Level A IVIVC dissolution results which accurately correlate with in vivo dissolution results are also provided.
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