Fructosylated puerarin, and preparation method and use thereof

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United States of America Patent

PATENT NO 8598128
APP PUB NO 20130190266A1
SERIAL NO

13820522

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Fructosylated puerarin being converted from puerarin by a bioconversion method conducted in an aqueous phase or nonaqueous phase system, including monofructosyl-(2,6)-puerarin, bifructosyl-(2,6)-puerarin, trifructosyl-(2,6)-puerarin, tetrafructosyl-(2,6)-puerarin and pentafructosyl-(2,6)-puerarin. Tests have shown that the oligosaccharylated puerarin is effective to treat acute myocardial ischemia, and can markedly suppress in vitro the proliferation of human breast cancer cell strain MDA-MB-23 and human chronmyelogenors leukemia cell strain K562, and it has a low toxicity.

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Patent OwnerAddress
NANJING UNIVERSITY OF TECHNOLOGY210000 PUZHU SOUTH ROAD PUKOU DISTRICT NANJING JIANGSU 30 NANJING CITY JIANGSU PROVINCE 210000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chu, Jianlin Jiangsu, CN 12 82
He, Bingfang Jiangsu, CN 3 1
Ouyang, Pingkai Jiangsu, CN 25 15
Wu, Bin Jiangsu, CN 269 4282
Wu, Xueming Jiangsu, CN 5 109
Zhang, Sen Jiangsu, CN 105 329

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