Glycosylated indolocarbazoles, method for obtaining same and uses thereof
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United States of America Patent
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Dec 3, 2013
Grant Date -
Jun 9, 2011
app pub date -
Apr 6, 2009
filing date -
Apr 8, 2008
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Abstract
Glycosylated indolocarbazoles, method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.
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