Trypsin-like serine protease inhibitors, and their preparation and use

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United States of America Patent

PATENT NO 8598206
APP PUB NO 20110301196A1
SERIAL NO

13015734

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Abstract

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The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.

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Patent Owner(s)

Patent OwnerAddress
THE MEDICINES COMPANY (LEIPZIG) GMBHLEIPZIG GERMANY LEIPZIG FREE STATE OF SAXONY

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daghish, Mohammed Leipzig, DE 8 31
Herold, Peter Münchenstein, CH 85 550
Jelakovic, Stjepan Freiburg, DE 25 36
Ludwig, Friedrich-Alexander Leipzig, DE 7 36
Reichelt, Claudia Leipzig, DE 9 59
Schulze, Alexander Bad Liebenwerda, DE 13 98
Schweinitz, Andrea Jena, DE 18 142

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