Peptides, compositions and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8614187
APP PUB NO 20120295851A1
SERIAL NO

13530550

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Abstract

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Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.

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Patent Owner(s)

Patent OwnerAddress
THE QUEEN'S UNIVERSITY OF BELFASTBELFAST COUNTY ANTRIM BT7 1NN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Tianbao Belfast, GB 4 9
Hirst, David Belfast, GB 14 160
O'Rourke, Martin Belfast, GB 3 9
Shaw, Christopher Belfast, GB 28 163
Walker, Brian Belfast, GB 67 786

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