Aβ binding molecules

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United States of America Patent

PATENT NO 8623365
APP PUB NO 20120114560A1
SERIAL NO

13332753

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention encompasses isolated antibodies, or fragments thereof, that are humanized variants of murine antibody 266 which employ complementarity determining regions derived from murine antibody 266. The variant antibodies are useful for treatment or prevention of conditions and diseases associated with Aβ, including Alzheimer's disease, Down's syndrome, cerebral amyloid angiopathy, mild cognitive impairment, and the like.

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Patent Owner(s)

  • APPLIED MOLECULAR EVOLUTION, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Davies, Julian La Jolla, US 33 464
Tang, Ying San Diego, US 106 741
Watkins, Jeffry Dean Encinitas, US 37 1520

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