Process for the preparation of strontium ranelate
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United States of America Patent
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Jan 7, 2014
Grant Date -
Aug 27, 2009
app pub date -
Aug 18, 2006
filing date -
Aug 19, 2005
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Abstract
A process for the preparation of strontium ranelate or a hydrate thereof is provided comprising (a) reacting a tetraester compound of Formula II: wherein R, R1, R2, and R3 are independently a linear or branched C1-C6 alkyl group or a substituted or unsubstituted C3-C12 cyclic group, in the presence of a lithium base and in a solvent with an inorganic acid salt of strontium.
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