Gene expression markers for prediction of patient response to chemotherapy
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United States of America Patent
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Jan 21, 2014
Grant Date -
Feb 16, 2012
app pub date -
Oct 21, 2011
filing date -
Mar 14, 2008
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Abstract
The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material.
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