Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine
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United States of America Patent
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Jan 21, 2014
Grant Date -
Aug 21, 2008
app pub date -
Jun 19, 2006
filing date -
Jun 17, 2005
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Abstract
The present invention relates to method for selective reduction and derivatization of recombinantly prepared engineered proteins comprising at least one non-native cysteine, wherein the reduction reaction is conducted in the presence of a redox buffer or in the presence of a triarylphosphine reducing agent.
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