Prevention and treatment of amyloidogenic disease

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United States of America Patent

PATENT NO 8642044
APP PUB NO 20090191231A1
SERIAL NO

11842116

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Abstract

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The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of Aβ and antibodies binding to the same.

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Patent Owner(s)

  • JANSSEN ALZHEIMER IMMUNOTHERAPY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Schenk, Dale B Burlingame, US 133 5576
Vasquez, Nicki San Francisco, US 10 244
Yednock, Theodore Forest Knolls, US 28 662

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