Enhanced moisture barrier immediate release film coating systems and substrates coated therewith
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United States of America Patent
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Feb 11, 2014
Grant Date -
Nov 18, 2010
app pub date -
Apr 28, 2010
filing date -
May 12, 2009
priority date (Note) -
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Abstract
The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.
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