PDX1 expressing endoderm

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United States of America Patent

PATENT NO 8647873
APP PUB NO 20090011502A1
SERIAL NO

11587735

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Abstract

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Disclosed herein are cell cultures comprising PDX1-positive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified PDX1-positive endoderm cells as well as methods for enriching, isolating and purifying PDX1-positive endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of endoderm cells, such as PDX1-positive foregut endoderm cells and PDX1-negative definitive endoderm cells, are also disclosed.

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Patent Owner(s)

  • VIACYTE, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agulnick, Alan D San Diego, US 49 1873
Baetge, Emmanuel E Encinitas, US 45 1730
D'Amour, Kevin Allen San Diego, US 41 1419
Eliazer, Susan San Diego, US 23 666

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