Pharmaceutical composition of nanoparticles
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United States of America Patent
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Mar 4, 2014
Issued Date -
N/A
app pub date -
Nov 21, 2012
filing date -
Oct 5, 2004
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Abstract
The invention discloses a pharmaceutical composition of pH-sensitive liposome nanoparticles for lodging in a target tissue cell in situ of an animal subject, the nanoparticles comprising a proton-releasing photosensitive compound that releases protons upon photolysis, wherein the compound is in vesicles of the liposomes. A light or UV light is provided to induce the photosensitive compound to release the protons, thus the released protons causing the pH-sensitive liposome to decompose.
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