Use of two microRNA moleculars in lung cancer prognosis and medicine preparation

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United States of America Patent

PATENT NO 8664191
APP PUB NO 20120220644A1
SERIAL NO

13382686

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Abstract

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The present invention relates to use of two microRNAs in detection of lung cancer prognosis and in medicine preparation. Particularly, the invention relates to a composition comprising two small RNA molecules microRNA-150 and microRNA-886-3p, a device comprising the composition used in detection of lung cancer prognosis and in preparation of medicaments for inhibiting mammal and human lung cancer metastasis. Specifically, the expression levels of microRNA-150 and microRNA-886-3p can be used as the prognostic criteria of lung cancer prognosis, wherein high expression level of the gene combination indicates favorable therapeutic effect. The invention also relates to a device detecting the expression levels of microRNA-150 and microRNA-886-3p in mammalian and human lung cancer and a method for detecting the expression levels of microRNA-150 and microRNA-886-3p in samples.

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Patent Owner(s)

Patent OwnerAddress
CANCER INSTITUTE CHINESE ACADEMY OF MEDICAL SCIENCES100021 BEIJING CHAOYANG DISTRICT PANJIAYUAN BEIJING CITY BEIJING CITY 100021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bi, Nan Beijing, CN 1 0
Cao, Jianzhong Beijing, CN 2 3
Liu, Wenyang Beijing, CN 7 4
Song, Yongmei Beijing, CN 1 0
Wang, Lühua Beijing, CN 1 0
Zhan, Qimin Beijing, CN 5 6

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