Use of two microRNA moleculars in lung cancer prognosis and medicine preparation
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United States of America Patent
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Mar 4, 2014
Grant Date -
Aug 30, 2012
app pub date -
Jul 9, 2009
filing date -
Jul 9, 2009
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Abstract
The present invention relates to use of two microRNAs in detection of lung cancer prognosis and in medicine preparation. Particularly, the invention relates to a composition comprising two small RNA molecules microRNA-150 and microRNA-886-3p, a device comprising the composition used in detection of lung cancer prognosis and in preparation of medicaments for inhibiting mammal and human lung cancer metastasis. Specifically, the expression levels of microRNA-150 and microRNA-886-3p can be used as the prognostic criteria of lung cancer prognosis, wherein high expression level of the gene combination indicates favorable therapeutic effect. The invention also relates to a device detecting the expression levels of microRNA-150 and microRNA-886-3p in mammalian and human lung cancer and a method for detecting the expression levels of microRNA-150 and microRNA-886-3p in samples.

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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
CANCER INSTITUTE CHINESE ACADEMY OF MEDICAL SCIENCES | 100021 BEIJING CHAOYANG DISTRICT PANJIAYUAN BEIJING CITY BEIJING CITY 100021 |
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Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Bi, Nan | Beijing, CN | 1 | 0 |
Cao, Jianzhong | Beijing, CN | 2 | 3 |
Liu, Wenyang | Beijing, CN | 7 | 4 |
Song, Yongmei | Beijing, CN | 1 | 0 |
Wang, Lühua | Beijing, CN | 1 | 0 |
Zhan, Qimin | Beijing, CN | 5 | 6 |
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11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Sep 4, 2025 |
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Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
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