Methods of determining levels of free amino acids and dipeptides and diagnosing Alzheimer's disease
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United States of America Patent
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Mar 11, 2014
Grant Date -
Apr 28, 2011
app pub date -
Aug 17, 2007
filing date -
Aug 18, 2006
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Abstract
Provided herein are methods of diagnosing Alzheimer's disease (“AD”) based on characteristic changes of the levels of certain free amino acids or dipeptides (collectively termed as “AD diagnosis markers”) in the body fluid sample of an individual, carnosine synthesis activities in the plasma, and dopamine synthesis activities in the plasma. Also provided are methods of simultaneously determining the levels of at least two free amino acids or dipeptides in the biological fluid sample of an individual.
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