Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens

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United States of America Patent

PATENT NO 8673332
SERIAL NO

13560538

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Abstract

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A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.

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Patent Owner(s)

  • THE SPECTRANETICS CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lerner, Daniel J Scarsdale, US 10 316
Michal, Eugene T San Francisco, US 79 3273
Pollman, Matthew J San Francisco, US 21 529

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