Anti-ferroportin 1 monoclonal antibodies and uses thereof

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United States of America Patent

PATENT NO 8679497
SERIAL NO

13465462

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Abstract

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Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.

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Patent Owner(s)

  • ELI LILLY AND COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leung, Donmienne Doen Mun San Diego, US 17 35
Luan, Peng Livermore, US 23 72
Manetta, Joseph Vincent Indianapolis, US 5 23
Tang, Ying San Diego, US 106 741
Witcher, Derrick Ryan Fishers, US 30 95

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