Axial and radial flow columns with inflatable seals to facilitate packing and unpacking
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United States of America Patent
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Apr 1, 2014
Grant Date -
N/A
app pub date -
Dec 21, 2012
filing date -
Dec 21, 2011
priority date (Note) -
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Abstract
A method, apparatus, and system are described to pack and unpack resin in a chromatography-column. One or more inflatable seals are deflated to pack a resin slurry from a bottom outlet valve into a resin bed chamber located between an outer shell of the column and an inner frit of the chromatography-column. The resin slurry is pumped into and through an outlet packing-and-running port and passed one or more deflated inflatable seals to pack the resin bed to a designated pressure with resin slurry. The inflatable seals are inflated to seal the resin bed in place.
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