Methods and compositions for in vitro and in vivo chondrogenesis
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United States of America Patent
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Apr 1, 2014
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Jul 16, 2010
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Jul 16, 2009
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Abstract
Aspects of the present invention include methods and compositions related to the production, identification and use of embryonic progenitor cell lines that are capable of undergoing chondrogenesis. A number of exemplary chondrogenic cell lines derived from primordial stem cells are disclosed. The chondrogenic cell lines described herein are robust, can expand for >40 passages, and have site-specific purity, thus providing for compositions and methods of producing diverse cartilage types with unique molecular compositions for use in research and therapy.
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