Viral purification methods
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United States of America Patent
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Apr 1, 2014
Grant Date -
Nov 22, 2007
app pub date -
Apr 17, 2007
filing date -
Apr 30, 2002
priority date (Note) -
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Abstract
The present invention is directed to an improved method of purifying virus, particularly reovirus. Infectious virus can be extracted from a cell culture with a detergent to produce high titers of virus, and the virus can then be purified by simple steps such as filtration and column chromatography. Viruses and compositions comprising the viruses prepared according to the present invention are also provided.
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