Methods, reagents, devices and instrumentation for preparing impregnated tissue samples suitable for histopathological and molecular studies

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8691165
APP PUB NO 20080206807A1
SERIAL NO

11997285

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Abstract

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A process for the production of paraffin sections of biological tissue, especially for molecular pathology studies is disclosed. In the process, the tissue sample is simultaneously fixed, dehydrated and cleared in a first step, subsequently dehydrated and cleared in a second step and infiltrated with an inert specimen matrix in a third step. The specimen can then be further embedded in a casting supporting matrix according to the standard procedures followed by any local pathology or research laboratory. A kit and a processing station for automating paraffin embedding of a tissue sample suitable for histopathological and molecular analysis is also described. A bio-indicator system is described for measuring the degree of crosslinking. A tissue sample holding means or a vial which includes a tissue sample holding means provided with a data logging device capable of registering and transmitting data regarding the sample and conditions where the sample was processed is also disclosed.

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Patent Owner(s)

  • HISTOGENEX N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Duymelinck, Carla Kruibeke, BE 2 24
Kockx, Mark Edegem, BE 2 0

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