Electron transfer dissociation for biopolymer sequence analysis

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United States of America Patent

PATENT NO 8692187
APP PUB NO 20120184042A1
SERIAL NO

13422812

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Abstract

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The present invention relates to a new method for fragmenting ions in a mass spectrometer through the use of electron transfer dissociation, and for performing sequence analysis of peptides and proteins by mass spectrometry. In the case of peptides, the invention promotes fragmentation along the peptide backbone and makes it possible to deduce the amino acid sequence of the sample, including modified amino acid residues, through the use of an RF field device.

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Patent Owner(s)

  • UNIVERSITY OF VIRGINIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Coon, Joshua J Madison, US 22 442
Hunt, Donald F Charlottesville, US 46 333
Marto, Jarod A Wayland, US 2 6
Syka, John Edward Philip Charlottesville, US 10 329

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