Compositions comprising nanomaterials and method for using such compositions for histochemical processes

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United States of America Patent

PATENT NO 8703490
APP PUB NO 20110091897A1
SERIAL NO

12995790

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Abstract

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Histochemical process compositions comprising at least one nanoparticle in an amount effective to reduce or substantially eliminate the average number of spots per slide that result from a sample staining protocol are disclosed. Various nanoparticles, or combinations thereof, including metals, metal alloys, metal oxides, ceramics, functionalized metals or metalloids, and other miscellaneous nanoparticles, such as carbon nanoparticles and diamond nanoparticles, can be used. The nanoparticle concentration typically is from about 2 parts per million to about 20 parts per million. One embodiment of a disclosed method concerns applying a histochemical process composition to a sample, followed by performing a staining protocol on the sample. Particular embodiments concern dispensing a nanosolution onto a sample using an automated system, heating the sample, and performing a sample staining process.

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Patent Owner(s)

  • VENTANA MEDICAL SYSTEMS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cockayne, Scott Tucson, US 3 22
Ferrea, Heather Tucson, US 2 2
Herman, Michael Tucson, US 43 263
Hoben, Grace Marana, US 2 2
Jackson, Merrill Tucson, US 4 17
Sebastiao, Noemi Tucson, US 12 417

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