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United States of America Patent

PATENT NO 8715687
APP PUB NO 20120189650A1
SERIAL NO

13388715

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Abstract

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The present invention relates to ClfA polypeptides wherein amino acid Y474 or an amino acid adjacent to Y474 is mutated such that fibrinogen binding activity is decreased compared to an equivalent ClfA polypeptide without mutation of Y474 or an amino acid adjacent to Y474 as well as immunogenic compositions, vaccines, processes and uses of such mutated ClfA polypeptides.

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Patent Owner(s)

Patent OwnerAddress
GLAXOSMITHKLINE BIOLOGICALS S A1330 RIXENSART

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dequesne, Guy Rixensart, BE 10 51
Germain, Sophie Marie Jeanne Valentine Rixensart, BE 4 86

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