Gene expression signature of genomic instability in breast cancer

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United States of America Patent

PATENT NO 8741574
APP PUB NO 20110224089A1
SERIAL NO

13119101

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Abstract

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Methods of assessing genomic instability in breast cancer tissue by measuring the expression level of genes CDKN2A, SCYA18, STK15, NXF1, cDNA Dkfzp762M127, p28 KIAA0882, MYB, Human clone 23948, RERG, HNF3A, and ACADSB or a nucleic acid sequence comprising about 90% or greater sequence identity to SEQ ID NO: 21 in breast cancer tissue, an array suitable for use in such methods, and related methods and compositions.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES6011 EXECUTIVE BOULEVARD STE 325 NIH/OD/OIR/OTT MSC 7660 BETHESDA MD 20892-7660
WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION886 CHESTNUT RIDGE ROAD MORGANTOWN WV 26506

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Auer, Gert Solna, SE 11 84
Guo, Nancy Lan Morgantown, US 11 90
Habermann, Jens Celle, DE 4 9
Ried, Karl Thomas Bethesda, US 1 3

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