Gastric retentive extended release pharmaceutical compositions

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United States of America Patent

PATENT NO 8741885
SERIAL NO

13473571

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Abstract

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The present disclosure provides extended release pharmaceutical compositions comprising an opioid and an additional active pharmaceutical ingredient, wherein the composition exhibits gastric retentive properties which are achieved by a combination of a physical property of the composition and release of the opioid, wherein upon administration to a subject, the composition has at least one pharmacokinetic parameter that differs by less than about 30% when the subject is in a fasted state as compared to a fed state.

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Patent Owner(s)

  • MALLINCKRODT LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Devarakonda, Krishna St. Louis, US 9 118
Guiliani, Michael J Creve Coeur, US 2 26
Gupta, Vishal K Hillsborough, US 26 518
Heasley, Ralph A Webster Groves, US 41 550
Shelby, Susan Creve Coeur, US 16 232

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