Method for the solid phase-based production of phosphate-bridged nucleoside conjugates

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United States of America Patent

PATENT NO 8742094
SERIAL NO

13319108

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Abstract

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The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method, a cyclosaligenyl nucleotide is produced first, to which a linker is added, which is used to perform the immobilization on a solid phase. A subsequent reaction with corresponding nucleophiles results in the desired phosphate-bridged nucleoside conjugates, which can then again be cleaved from the solid phase-bound linker.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITAET HAMBURGMITTELWEG 177 HAMBURG 20148

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Meier, Chris Jork, DE 9 78
Tonn, Viktoria Caroline Hamburg, DE 1 13

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