Methods and compositions to modulate antiviral and immune activity responses

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United States of America Patent

PATENT NO 8747860
APP PUB NO 20130022602A1
SERIAL NO

13542581

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Abstract

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The invention is directed to an improved method to manufacture virus for use in vaccine by culturing infected cells that have been modified to overexpress miR-144. The invention is also directed to manipulating the activity or level of miR-144 in subjects in order to modulate the antiviral and immune response systems.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE FOR SYSTEMS BIOLOGY401 TERRY AVENUE NORTH SEATTLE WA 98109

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aderem, Alan A Seattle, US 5 21
Rosenberger, Carrie M San Francisco, US 3 19

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