Enhancing vessel lesion homing and repair potential of stem cells

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United States of America Patent

PATENT NO 8754056
SERIAL NO

12933482

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Abstract

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Disclosed herein are methods of enhancing repair of vascular lesions involving the administration of cells in which TGF-β expression and/or activity has been transiently blocked. Other methods involve the administration of a TGF-β blocking agent to a subject who has a vascular lesion or is at risk of developing a vascular lesion. Alternatively, a TGF-β blocking agent and treated cells are co-administered to a subject in need thereof.

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Patent Owner(s)

  • UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;BETASTEM THERAPEUTICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bartelmez, Stephen H Sausalito, US 7 98
Grant, Maria Gainesville, US 8 48

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