Anti-hepcidin antibodies and uses thereof

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United States of America Patent

PATENT NO 8765129
APP PUB NO 20130164304A1
SERIAL NO

13708059

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.

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Patent Owner(s)

  • ELI LILLY AND COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leung, Donmienne Doen Mun San Diego, US 17 35
Luan, Peng Livermore, US 23 72
Swanson, Barbara Anne Encinitas, US 7 48
Tang, Ying San Diego, US 106 741
Witcher, Derrick Ryan Fishers, US 30 95

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