Stable lipid-comprising drug delivery complexes and methods for their production
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United States of America Patent
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Jul 8, 2014
Grant Date -
Oct 24, 2013
app pub date -
Dec 12, 2012
filing date -
Jan 23, 1995
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Abstract
Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the prior art admixture method and upon purification, the complexes produced by the method of this invention are 50 to 500 fold more concentrated than the complexes formed by admixture. The method described herein provides for the large scale production of lipid-comprising drug delivery systems useful for gene therapy and other applications.
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