locus using zinc-finger nucleases

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United States of America Patent

PATENT NO 8771985
APP PUB NO 20120017290A1
SERIAL NO

13066802

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Abstract

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Disclosed herein are methods and compositions for genome editing of a Rosa locus, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.

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Patent Owner(s)

  • SANGAMO BIOSCIENCES, INC.;SIGMA-ALDRICH CO.;SIGMA-ALDVICH CO. LLC

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cui, Xiaoxia St. Louis, US 42 515
Davis, Gregory St. Louis, US 39 859
Gregory, Philip D Orinda, US 75 3037
Holmes, Michael C Oakland, US 87 3596
Weinstein, Edward J St. Louis, US 3 119

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