Vectors and yeast strains for protein production: Ca2+ ATPase overexpression

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United States of America Patent

PATENT NO 8771989
APP PUB NO 20130316403A1
SERIAL NO

13938603

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Abstract

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Lower eukaryote host cells in which an endogenous or heterologous Ca2+ ATPase is overexpressed are described. Also described are lower eukaryote host cells in which a calreticulin and/or ERp57 protein are overexpressed. These host cells are useful for producing recombinant glycoproteins that have reduced O-glycosylation.

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Patent Owner(s)

Patent OwnerAddress
GLYCOFI INCLEBANON NH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Byung-Kwon Norwich, US 62 729

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