Compounds having anti-adhesive effects on cancer cells

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United States of America Patent

PATENT NO 8785409
APP PUB NO 20100113571A1
SERIAL NO

12524844

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Abstract

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Compounds of the form O-(x-L)n, where O is an oligonucleoside having at least a plurality of N3′→P5′ thiophosphoramidate (NPS) internucleoside linkages, a conjugated lipid moiety L, and at least one G-rich sequence motif as described, are effective to morphologically alter and reduce adhesion of cancer cells.

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Patent Owner(s)

  • GERON CORPORATION;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gryaznov, Sergei M San Mateo, US 50 2475
Shay, Jerry W Dallas, US 15 145
Wright, Woodring Arlington, US 15 269

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