Methods of treating psoriasis using IL-17 receptor A antibodies
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United States of America Patent
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Jul 29, 2014
Grant Date -
Oct 4, 2012
app pub date -
May 15, 2012
filing date -
Oct 2, 2006
priority date (Note) -
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Abstract
The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
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