Stable, dried rotavirus vaccine, compositions and process for preparation thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8795686
APP PUB NO 20110177119A1
SERIAL NO

13056557

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Abstract

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The present invention provides novel lyophilized rotavirus vaccine formulations and methods of their preparation. The formulations include vaccine stabilizers, resulting in a vaccine formulation with enhanced stability and minimal loss of potency. The rotavirus vaccine formulations comprise an advantageous ratio of a disaccharide (such as sucrose) to an amino acid (such as glycine). The lyophilization results in a virus formulation with 100% virus preservation and residual moisture from about 0.8% to 1.4%.

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Patent Owner(s)

Patent OwnerAddress
SERUM INSTITUTE OF INDIA PRIVATE LIMITEDPUNE 411 028 MAH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dhere, Rajeev M Pune, IN 1 4
Pisal, Sambhaji S Pune, IN 1 4
Zade, Jagdish K Pune, IN 1 4

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