1,2-benzisothiazol-3-one compound production method
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United States of America Patent
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Aug 12, 2014
Grant Date -
Dec 26, 2013
app pub date -
Feb 22, 2012
filing date -
Mar 18, 2011
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Abstract
The present invention provides a method for producing 1,2-benzisothiazol-3-one compounds by reacting a 2-(alkylthio)benzonitrile compound with a halogenating agent in the presence of water, the method being characterized in that the reaction proceeds while the halogenating agent and water are gradually and simultaneously added to a reaction system containing the 2-(alkylthio)benzonitrile compound. The invention allows the simple and economical production of highly pure 1,2-benzisothiazol-3-one compounds, which are useful as antimicrobial agents, antifungal agents, etc.
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