Chromatographic process for the production of highly purified polyunsaturated fatty acids
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United States of America Patent
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Aug 12, 2014
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N/A
app pub date -
May 17, 2013
filing date -
May 7, 2013
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Abstract
A process is provided for recovering a first polyunsaturated fatty acid (PUFA) from a feed mixture including at least one additional fatty acid (e.g., a second fatty acid (FA)). The process optionally comprises:
- performing a main step of chromatographic separation using an aqueous organic eluent and collecting a first stream of eluent enriched in the first PUFA and a second stream of eluent enriched in the second FA;subjecting the second stream of eluent to a concentration step to obtain a concentrated portion including the second FA, and a depleted portion comprising eluent, but depleted of the second FA. The water-to-organic ratio of the depleted portion is lower than the water-to-organic ratio of the second stream of eluent. The process also includes:at least partially recycling the depleted portion for use in the main step of chromatographic separation.
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