Irreversible electroporation using nanoparticles

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United States of America Patent

PATENT NO 8814860
APP PUB NO 20130281968A1
SERIAL NO

13919640

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Abstract

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The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.

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Patent Owner(s)

Patent OwnerAddress
VIRGINIA TECH INTELLECTUAL PROPERTIES INCVIRGINIA TECH HOLTZMAN ALUMNI CENTER 3RD FLOOR 901 PRICES FORK ROAD BLACKBURG VA 24061

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arena, Christopher B Burlington, US 19 1781
Davalos, Rafael V Blacksburg, US 69 3808
Lee, Yong Woo Blacksburg, US 73 423
Rylander, Marissa N Blacksburg, US 3 293

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